DendroBLAST is a very simple method for transforming BLAST bit scores from an all-vs-all BLAST searche into a phylogenetic trees of genes. Its remarkably accurate given its limited inputs and thus enables large scale phylogenetic comparisons and analyses such as OrthoFinder to be implemented in reasonable time scales.

If you use DendroBLAST in your work please cite:

Kelly S and Maini PK (2013). DendroBLAST: Approximate Phylogenetic Trees in the Absence of Multiple Sequence Alignments. PLOS One 8(3): e58537